A 16th minute strike by captain Joseph Tetteh Zutah handed the home side all three points to maintain their unbeaten run in their last four matches in the league.
Midfield dynamo Kwasi Donsu sent in a beautiful chip for Zutah to head home to break the virginity of the game.
The Capelli Boys fought gallantly for the equalizer but both sides went for the break with Medeama having the advantage.
It is back-to-back wins after the 2-1
Watch Joseph Tetteh Zutah’s header which gave Medeama a 1-0 win over Inter Allies